Womelsdorf, named after John Womelsdorff, is a borough in Berks County, Pennsylvania, United States. The population was 2,810 at the 2010 census. The main thoroughfares through Womelsdorf are High Street, which runs east-west, and Pennsylvania Route 419, which runs north-south. U.S. Route 422 runs along the northern edge of town. A Pennsylvania state historic site, the Conrad Weiser Homestead, is located in Womelsdorf; this site interprets the life of Conrad Weiser, a well-known 18th-century German immigrant who played a major role in the history of colonial Pennsylvania.